Al-Mefty's Meningiomas by Franco DeMonte, Michael W. McDermott, Ossama Al-Mefty

By Franco DeMonte, Michael W. McDermott, Ossama Al-Mefty

This is a superb booklet and a wanted replace. For
anyone drawn to learning this particular neoplasm in depth,this e-book is
worthwhile. it's a must-have in all neurosurgery, neurology, and radiology
libraries. -- Doody's Review

Al-Mefty's Meningiomas, moment Edition is the definitive advisor to
meningioma analysis, remedy, and surgical procedure, and displays over a decade of
major advances within the prognosis and administration of either intracranial and spinal
meningiomas because the first version used to be published.


  • New to this variation: info on molecular
    biology, usual background and progress premiums, the increase of radiosurgery as a
    possible remedy alternative, and masses extra

  • Over 500 top quality radiographic photos and
    full-color illustrations show anatomy and surgical procedure

  • In-depth insurance of intraoperative MRI and
    endoscopic resection

  • Key subject matters usually lacking from different meningiomas texts together with caseload administration, and postoperative caliber of lifestyles issues

This landmark reference will improve the precision and surgical talents of each clinician or resident in neurosurgery or neurology.

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Additional info for Al-Mefty's Meningiomas

Example text

A thicker, looser collection of mesenchymal cells further covers the neural tube starting around day 24 to 28 and completely envelops the developing spinal cord and brain by day 33 to 41. 4,6,7 2/24/11 11:02 AM As the pluripotent meninx primitiva develops, it subdivides into two distinct layers between days 34 and 48. The outer portion, the ectomeninx, is dense and compact, whereas the inner layer, the endomeninx, is more loosely arranged. The ectomeninx is the precursor to the dura and the bones of the neurocranium, thus the close apposition of dura and skull stems from their shared embryological ancestry.

1 Because they originate from meningothelial cells found in the arachnoid layer of the meninges, the successful management of meningiomas demands comprehensive understanding of the anatomy of the meninges. Knowledge of meningeal architecture and its osseous and neurovascular relationships provides the basis for understanding the sites of origin and the routes of spread of meningiomas. Successful operative strategies must account for both the tumor itself and its dural attachments. 2 Familiarity with meningeal anatomy allows for the design of safe surgical approaches to complex regions of the cranial base while minimizing neurovascular injuries.

Cytological and cytogenetical studies on human meningioma. Cancer Genet Cytogenet 1982;6(3):249–274 94. Seizinger BR, de la Monte S, Atkins L, Gusella JF, Martuza RL. Molecular genetic approach to human meningioma: loss of genes on chromosome 22. Proc Natl Acad Sci U S A 1987;84(15):5419–5423 95. Takahashi JA, Mori H, Fukumoto M, et al. Gene expression of fibroblast growth factors in human gliomas and meningiomas: demonstration of cellular source of basic fibroblast growth factor mRNA and peptide in tumor tissues.

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